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CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring

OBJECTIVE: The aim of our study was to evaluate the differences between sclerotherapy with and without ethanol concentration monitoring for the treatment of simple renal cysts. MATERIALS AND METHODS: Sixty-seven patients with 70 simple renal cysts were randomly assigned to two groups in a 12-month p...

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Autores principales: Yu, Jin Hong, Du, Yong, Li, Yang, Yang, Han Feng, Xu, Xiao Xue, Zheng, Hou Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909866/
https://www.ncbi.nlm.nih.gov/pubmed/24497796
http://dx.doi.org/10.3348/kjr.2014.15.1.80
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author Yu, Jin Hong
Du, Yong
Li, Yang
Yang, Han Feng
Xu, Xiao Xue
Zheng, Hou Jun
author_facet Yu, Jin Hong
Du, Yong
Li, Yang
Yang, Han Feng
Xu, Xiao Xue
Zheng, Hou Jun
author_sort Yu, Jin Hong
collection PubMed
description OBJECTIVE: The aim of our study was to evaluate the differences between sclerotherapy with and without ethanol concentration monitoring for the treatment of simple renal cysts. MATERIALS AND METHODS: Sixty-seven patients with 70 simple renal cysts were randomly assigned to two groups in a 12-month prospective controlled trial. One group (group A) was treated with computed tomography (CT)-guided sclerotherapy without ethanol concentration monitoring (33 patients with 35 cysts), whereas the other group (group B) had ethanol concentration monitoring (34 patients with 35 cysts) during the procedure. Treatment outcomes between the two groups were compared 12 months later with follow-up ultrasound examination. RESULTS: After the 12-month follow-up period, the overall success rate was 74.3% in group A and 94.3% in group B (p = 0.022). The mean cyst size before and after treatment was 8.6 ± 2.0 cm and 2.3 ± 2.9 cm, respectively, in group A, and 8.4 ± 1.7 cm and 0.8 ± 1.9 cm, respectively, in group B. The final size of the cysts in group B was significantly smaller than that in group A (p = 0.015). The likelihood of treatment with ethanol concentration monitoring being successful was approximately 16 times higher than without ethanol concentration monitoring (p = 0.026; odds ratio = 15.7; 95% confidence interval: 1.38-179.49). There were no major complications in either group. CONCLUSION: Monitoring of Hounsfield units (HU) of ethanol by CT is an effective method in the treatment of simple renal cysts with ethanol sclerotherapy. The ethanol sclerotherapy procedure can be terminated at the point of clear fluid aspiration because the HU (-190) of CT scan corresponds to it.
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spelling pubmed-39098662014-02-04 CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring Yu, Jin Hong Du, Yong Li, Yang Yang, Han Feng Xu, Xiao Xue Zheng, Hou Jun Korean J Radiol Intervention OBJECTIVE: The aim of our study was to evaluate the differences between sclerotherapy with and without ethanol concentration monitoring for the treatment of simple renal cysts. MATERIALS AND METHODS: Sixty-seven patients with 70 simple renal cysts were randomly assigned to two groups in a 12-month prospective controlled trial. One group (group A) was treated with computed tomography (CT)-guided sclerotherapy without ethanol concentration monitoring (33 patients with 35 cysts), whereas the other group (group B) had ethanol concentration monitoring (34 patients with 35 cysts) during the procedure. Treatment outcomes between the two groups were compared 12 months later with follow-up ultrasound examination. RESULTS: After the 12-month follow-up period, the overall success rate was 74.3% in group A and 94.3% in group B (p = 0.022). The mean cyst size before and after treatment was 8.6 ± 2.0 cm and 2.3 ± 2.9 cm, respectively, in group A, and 8.4 ± 1.7 cm and 0.8 ± 1.9 cm, respectively, in group B. The final size of the cysts in group B was significantly smaller than that in group A (p = 0.015). The likelihood of treatment with ethanol concentration monitoring being successful was approximately 16 times higher than without ethanol concentration monitoring (p = 0.026; odds ratio = 15.7; 95% confidence interval: 1.38-179.49). There were no major complications in either group. CONCLUSION: Monitoring of Hounsfield units (HU) of ethanol by CT is an effective method in the treatment of simple renal cysts with ethanol sclerotherapy. The ethanol sclerotherapy procedure can be terminated at the point of clear fluid aspiration because the HU (-190) of CT scan corresponds to it. The Korean Society of Radiology 2014 2014-01-08 /pmc/articles/PMC3909866/ /pubmed/24497796 http://dx.doi.org/10.3348/kjr.2014.15.1.80 Text en Copyright © 2014 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Intervention
Yu, Jin Hong
Du, Yong
Li, Yang
Yang, Han Feng
Xu, Xiao Xue
Zheng, Hou Jun
CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title_full CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title_fullStr CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title_full_unstemmed CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title_short CT-Guided Sclerotherapy for Simple Renal Cysts: Value of Ethanol Concentration Monitoring
title_sort ct-guided sclerotherapy for simple renal cysts: value of ethanol concentration monitoring
topic Intervention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909866/
https://www.ncbi.nlm.nih.gov/pubmed/24497796
http://dx.doi.org/10.3348/kjr.2014.15.1.80
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