Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1

Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene expression in the liver. Hyperinsulinemia induces transcription of SREBP-1c...

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Detalles Bibliográficos
Autores principales: Jung, Yun-A, Kim, Hee Kyoung, Bae, Kwi-Hyun, Seo, Hye-Young, Kim, Hye-Soon, Jang, Byoung Kuk, Jung, Gwon-Soo, Lee, In-Kyu, Kim, Mi-Kyung, Park, Keun-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909891/
https://www.ncbi.nlm.nih.gov/pubmed/24458133
http://dx.doi.org/10.1038/emm.2013.143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909891/
https://www.ncbi.nlm.nih.gov/pubmed/24458133
http://dx.doi.org/10.1038/emm.2013.143

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