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Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1

Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene expression in the liver. Hyperinsulinemia induces transcription of SREBP-1c...

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Detalles Bibliográficos
Autores principales:	Jung, Yun-A, Kim, Hee Kyoung, Bae, Kwi-Hyun, Seo, Hye-Young, Kim, Hye-Soon, Jang, Byoung Kuk, Jung, Gwon-Soo, Lee, In-Kyu, Kim, Mi-Kyung, Park, Keun-Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909891/ https://www.ncbi.nlm.nih.gov/pubmed/24458133 http://dx.doi.org/10.1038/emm.2013.143

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