Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens

BACKGROUND: Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during a single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation of genomic changes with a “one-off” catastrophic eve...

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Detalles Bibliográficos
Autores principales: Cai, Haoyang, Kumar, Nitin, Bagheri, Homayoun C, von Mering, Christian, Robinson, Mark D, Baudis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909908/
https://www.ncbi.nlm.nih.gov/pubmed/24476156
http://dx.doi.org/10.1186/1471-2164-15-82

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