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Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population

BACKGROUND: Genetic variation associated with human leukocyte antigen (HLA) genes has immunological functions and is associated with autoimmune diseases. To date, large-scale studies involving classical HLA genes have been limited by time-consuming and expensive HLA-typing technologies. To reduce th...

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Detalles Bibliográficos
Autores principales: Hsieh, Ai-Ru, Chang, Su-Wei, Chen, Pei-Lung, Chu, Chen-Chung, Hsiao, Ching-Lin, Yang, Wei-Shiung, Chang, Chien-Ching, Wu, Jer-Yuarn, Chen, Yuan-Tsong, Chang, Tien-Chun, Fann, Cathy SJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909910/
https://www.ncbi.nlm.nih.gov/pubmed/24476119
http://dx.doi.org/10.1186/1471-2164-15-81