Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling

BACKGROUND: Deregulation of Wnt/β-catenin signaling is a hallmark of the majority of sporadic forms of colorectal cancer and results in increased stability of the protein β-catenin. β-catenin is then shuttled into the nucleus where it activates the transcription of its target genes, including the pr...

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Detalles Bibliográficos
Autores principales: Herbst, Andreas, Jurinovic, Vindi, Krebs, Stefan, Thieme, Susanne E, Blum, Helmut, Göke, Burkhard, Kolligs, Frank T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909937/
https://www.ncbi.nlm.nih.gov/pubmed/24467841
http://dx.doi.org/10.1186/1471-2164-15-74

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