Cargando…

Metabotropic Glutamate Receptor 1 (Grm1) Is An Oncogene In Epithelial Cells

Non-neuronal expression of components of the glutamatergic system has been increasingly observed, and our laboratory previously had demonstrated the etiological role of ectopically expressed metabotropic glutamate receptor 1 (Grm1/mGluR1) in mouse models of melanoma. We hypothesize that inappropriat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martino, Jeffrey J, Wall, Brian A, Mastrantoni, Elisa, Wilimczyk, Barbara J, La Cava, Stephanie N, Degenhardt, Kurt, White, E, Chen, Suzie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910169/ https://www.ncbi.nlm.nih.gov/pubmed/23085756 http://dx.doi.org/10.1038/onc.2012.471

Ejemplares similares

Exosomes released by metabotropic glutamate receptor 1 (GRM1) expressing melanoma cells increase cell migration and invasiveness
por: Isola, Allison L., et al.
Publicado: (2017)

The role of group II metabotropic glutamate receptors in cognition and anxiety: Comparative studies in GRM2(−/−), GRM3(−/−) and GRM2/3(−/−) knockout mice
por: De Filippis, Bianca, et al.
Publicado: (2015)

Loss-of-Function Models of the Metabotropic Glutamate Receptor Genes Grm8a and Grm8b Display Distinct Behavioral Phenotypes in Zebrafish Larvae (Danio rerio)
por: Lüffe, Teresa M., et al.
Publicado: (2022)

The glutamate metabotropic receptor 5 (GRM5) gene is associated with beef cattle home range and movement tortuosity
por: Moreno García, Cristian A., et al.
Publicado: (2022)

Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice
por: Lyon, Louisa, et al.
Publicado: (2008)

Investigation of genetic variants regulating the expression of metabotropic glutamate receptor, subtype 5 (GRM5) mRNA in human brain
por: Wang, Jian, et al.
Publicado: (2012)

Allelic Association, DNA Resequencing and Copy Number Variation at the Metabotropic Glutamate Receptor GRM7 Gene Locus in Bipolar Disorder
por: Kandaswamy, Radhika, et al.
Publicado: (2014)

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo
por: Chen, Ho-Chung, et al.
Publicado: (2017)

U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo
por: Goraczniak, Rafal, et al.
Publicado: (2013)

Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study
por: García-Bea, Aintzane, et al.
Publicado: (2016)

Cellular and cytokine-dependent immunosuppressive mechanisms of grm1-transgenic murine melanoma
por: Alb, Miriam, et al.
Publicado: (2012)

A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding
por: García-Bea, Aintzane, et al.
Publicado: (2017)

Deleterious GRM1 Mutations in Schizophrenia
por: Ayoub, Mohammed Akli, et al.
Publicado: (2012)

Metabotropic Glutamate Receptor 1 Expression and Its Polymorphic Variants Associate with Breast Cancer Phenotypes
por: Mehta, Madhura S., et al.
Publicado: (2013)

Metabotropic glutamate receptors inhibit microglial glutamate release
por: McMullan, Stephen M, et al.
Publicado: (2012)

Structural Insights into Metabotropic Glutamate Receptor Activation
por: Koehl, Antoine, et al.
Publicado: (2019)

Optical Control of Metabotropic Glutamate Receptors
por: Levitz, Joshua, et al.
Publicado: (2013)

Kinetic fingerprinting of metabotropic glutamate receptors
por: Kukaj, Taulant, et al.
Publicado: (2023)

Constitutive activity of metabotropic glutamate receptor 7
por: Kammermeier, Paul J
Publicado: (2015)

Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p
por: Xiao, Bin, et al.
Publicado: (2019)

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia
por: Maksymetz, James, et al.
Publicado: (2017)

Implications of a Neuronal Receptor Family, Metabotropic Glutamate Receptors, in Cancer Development and Progression
por: Eddy, Kevinn, et al.
Publicado: (2022)

Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins
por: Kammermeier, Paul J
Publicado: (2006)

Allosteric Modulators of Metabotropic Glutamate Receptors as Novel Therapeutics for Neuropsychiatric Disease
por: Luessen, Deborah J., et al.
Publicado: (2022)

An Essential Role of Fyn in the Modulation of Metabotropic Glutamate Receptor 1 in Neurons
por: Jin, Dao-Zhong, et al.
Publicado: (2017)

Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
por: Pronot, Marie, et al.
Publicado: (2022)

Fractionation of Spatial Memory in GRM2/3 (mGlu2/mGlu3) Double Knockout Mice Reveals a Role for Group II Metabotropic Glutamate Receptors at the Interface Between Arousal and Cognition
por: Lyon, Louisa, et al.
Publicado: (2011)

Metabotropic Glutamate Receptor-1 Contributes to Progression in Triple Negative Breast Cancer
por: Banda, Malathi, et al.
Publicado: (2014)

circ-Grm1 promotes pulmonary artery smooth muscle cell proliferation and migration via suppression of GRM1 expression by FUS
por: Sun, Shijing, et al.
Publicado: (2021)

Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells
por: Dolfi, Sonia C, et al.
Publicado: (2017)

Therapeutic promise and principles: Metabotropic glutamate receptors
por: Maiese, Kenneth, et al.
Publicado: (2008)

Therapeutic Potential of Metabotropic Glutamate Receptor Modulators
por: Hovelsø, N, et al.
Publicado: (2012)

Homology modelling of metabotropic glutamate receptor 2
por: Mordalski, S, et al.
Publicado: (2011)

Metabotropic Glutamate Receptors for Parkinson's Disease Therapy
por: Gasparini, Fabrizio, et al.
Publicado: (2013)

Metabotropic Glutamate Receptors and Interacting Proteins in Epileptogenesis
por: Qian, Feng, et al.
Publicado: (2016)

The Role of Metabotropic Glutamate Receptor Genes in Schizophrenia
por: Maj, Carlo, et al.
Publicado: (2016)

Special Issue on Metabotropic Glutamate Receptors: Editorial
por: Salt, Prof. Thomas E.
Publicado: (2016)

Role of Metabotropic Glutamate Receptors in Neurological Disorders
por: Crupi, Rosalia, et al.
Publicado: (2019)

Metabotropic glutamate receptor 5 in bulimia nervosa
por: Mihov, Yoan, et al.
Publicado: (2020)

Allosteric Molecular Switches in Metabotropic Glutamate Receptors
por: Orgován, Zoltán, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5emukfpf6n7bqidutbg68gcsvb