Cancer drugs inhibit morphogenesis in the human fungal pathogen, Candida albicans

Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive ca...

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Detalles Bibliográficos
Autores principales: Routh, Madhushree M, Chauhan, Nitin M, Karuppayil, S Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Microbiology 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910200/
https://www.ncbi.nlm.nih.gov/pubmed/24516452
Descripción
Sumario:Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive candidiasis. In this study, we report the antimorphogenetic properties of thirty cancer drugs.

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