Cargando…

Association between Hypertension and Periodontitis: Possible Mechanisms

This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxida...

Descripción completa

Detalles Bibliográficos
Autores principales: Leong, Xin-Fang, Ng, Chun-Yi, Badiah, Baharin, Das, Srijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910336/
https://www.ncbi.nlm.nih.gov/pubmed/24526921
http://dx.doi.org/10.1155/2014/768237
_version_ 1782301965683785728
author Leong, Xin-Fang
Ng, Chun-Yi
Badiah, Baharin
Das, Srijit
author_facet Leong, Xin-Fang
Ng, Chun-Yi
Badiah, Baharin
Das, Srijit
author_sort Leong, Xin-Fang
collection PubMed
description This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension. Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and periodontitis. However, more well-designed prospective population trials need to be carried out to ascertain the role of periodontitis in hypertension.
format Online
Article
Text
id pubmed-3910336
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-39103362014-02-13 Association between Hypertension and Periodontitis: Possible Mechanisms Leong, Xin-Fang Ng, Chun-Yi Badiah, Baharin Das, Srijit ScientificWorldJournal Review Article This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension. Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and periodontitis. However, more well-designed prospective population trials need to be carried out to ascertain the role of periodontitis in hypertension. Hindawi Publishing Corporation 2014-01-08 /pmc/articles/PMC3910336/ /pubmed/24526921 http://dx.doi.org/10.1155/2014/768237 Text en Copyright © 2014 Xin-Fang Leong et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Leong, Xin-Fang
Ng, Chun-Yi
Badiah, Baharin
Das, Srijit
Association between Hypertension and Periodontitis: Possible Mechanisms
title Association between Hypertension and Periodontitis: Possible Mechanisms
title_full Association between Hypertension and Periodontitis: Possible Mechanisms
title_fullStr Association between Hypertension and Periodontitis: Possible Mechanisms
title_full_unstemmed Association between Hypertension and Periodontitis: Possible Mechanisms
title_short Association between Hypertension and Periodontitis: Possible Mechanisms
title_sort association between hypertension and periodontitis: possible mechanisms
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910336/
https://www.ncbi.nlm.nih.gov/pubmed/24526921
http://dx.doi.org/10.1155/2014/768237
work_keys_str_mv AT leongxinfang associationbetweenhypertensionandperiodontitispossiblemechanisms
AT ngchunyi associationbetweenhypertensionandperiodontitispossiblemechanisms
AT badiahbaharin associationbetweenhypertensionandperiodontitispossiblemechanisms
AT dassrijit associationbetweenhypertensionandperiodontitispossiblemechanisms