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Association between Hypertension and Periodontitis: Possible Mechanisms
This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxida...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910336/ https://www.ncbi.nlm.nih.gov/pubmed/24526921 http://dx.doi.org/10.1155/2014/768237 |
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author | Leong, Xin-Fang Ng, Chun-Yi Badiah, Baharin Das, Srijit |
author_facet | Leong, Xin-Fang Ng, Chun-Yi Badiah, Baharin Das, Srijit |
author_sort | Leong, Xin-Fang |
collection | PubMed |
description | This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension. Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and periodontitis. However, more well-designed prospective population trials need to be carried out to ascertain the role of periodontitis in hypertension. |
format | Online Article Text |
id | pubmed-3910336 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39103362014-02-13 Association between Hypertension and Periodontitis: Possible Mechanisms Leong, Xin-Fang Ng, Chun-Yi Badiah, Baharin Das, Srijit ScientificWorldJournal Review Article This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension. Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and periodontitis. However, more well-designed prospective population trials need to be carried out to ascertain the role of periodontitis in hypertension. Hindawi Publishing Corporation 2014-01-08 /pmc/articles/PMC3910336/ /pubmed/24526921 http://dx.doi.org/10.1155/2014/768237 Text en Copyright © 2014 Xin-Fang Leong et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Leong, Xin-Fang Ng, Chun-Yi Badiah, Baharin Das, Srijit Association between Hypertension and Periodontitis: Possible Mechanisms |
title | Association between Hypertension and Periodontitis: Possible Mechanisms |
title_full | Association between Hypertension and Periodontitis: Possible Mechanisms |
title_fullStr | Association between Hypertension and Periodontitis: Possible Mechanisms |
title_full_unstemmed | Association between Hypertension and Periodontitis: Possible Mechanisms |
title_short | Association between Hypertension and Periodontitis: Possible Mechanisms |
title_sort | association between hypertension and periodontitis: possible mechanisms |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910336/ https://www.ncbi.nlm.nih.gov/pubmed/24526921 http://dx.doi.org/10.1155/2014/768237 |
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