In Vitro Characterization of Valproic Acid, ATRA, and Cytarabine Used for Disease-Stabilization in Human Acute Myeloid Leukemia: Antiproliferative Effects of Drugs on Endothelial and Osteoblastic Cells and Altered Release of Angioregulatory Mediators by Endothelial Cells

The combined use of the histone deacetylase inhibitor valproic acid (VPA), the retinoic acid receptor-α agonist all-trans retinoic acid (ATRA), and the deoxyribonucleic acid polymerase-α inhibitor cytarabine (Ara-C) is now considered for disease-stabilizing treatment of acute myeloid leukemia (AML)....

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Detalles Bibliográficos
Autores principales: Kvestad, Hilde, Evensen, Lasse, Lorens, James B., Bruserud, Øystein, Hatfield, Kimberley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910457/
https://www.ncbi.nlm.nih.gov/pubmed/24527217
http://dx.doi.org/10.1155/2014/143479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910457/
https://www.ncbi.nlm.nih.gov/pubmed/24527217
http://dx.doi.org/10.1155/2014/143479

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