Cargando…
Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence
Staphylococcus aureus subsp. anaerobius is responsible for Morel's disease in animals and a cause of abscess in humans. It is characterized by a microaerophilic growth, contrary to the other strains of S. aureus. The 2,604,446-bp genome (32.7% GC content) of S. anaerobius ST1464 comprises one c...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Michigan State University
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910551/ https://www.ncbi.nlm.nih.gov/pubmed/24501641 http://dx.doi.org/10.4056/sigs.3748294 |
_version_ | 1782301986543108096 |
---|---|
author | Elbir, Haitham Robert, Catherine Nguyen, Ti Thien Gimenez, Grégory El Sanousi, Sulieman M. Flock, Jan-Ingmar Raoult, Didier Drancourt, Michel |
author_facet | Elbir, Haitham Robert, Catherine Nguyen, Ti Thien Gimenez, Grégory El Sanousi, Sulieman M. Flock, Jan-Ingmar Raoult, Didier Drancourt, Michel |
author_sort | Elbir, Haitham |
collection | PubMed |
description | Staphylococcus aureus subsp. anaerobius is responsible for Morel's disease in animals and a cause of abscess in humans. It is characterized by a microaerophilic growth, contrary to the other strains of S. aureus. The 2,604,446-bp genome (32.7% GC content) of S. anaerobius ST1464 comprises one chromosome and no plasmids. The chromosome contains 2,660 open reading frames (ORFs), 49 tRNAs and three complete rRNAs, forming one complete operon. The size of ORFs ranges between 100 to 4,600 bp except for two ORFs of 6,417 and 7,173 bp encoding segregation ATPase and non-ribosomal peptide synthase, respectively. The chromosome harbors Staphylococcus phage 2638A genome and incomplete Staphylococcus phage genome PT1028, but no detectable CRISPRS. The antibiotic resistance gene for tetracycline was found although Staphylococcus aureus subsp. anaerobius is susceptible to tetracycline in-vitro. Intact oxygen detoxification genes encode superoxide dismutase and cytochrome quinol oxidase whereas the catalase gene is impaired by a stop codon. Based on the genome, in-silico multilocus sequence typing indicates that S. aureus subsp. anaerobius emerged as a clone separated from all other S. aureus strains, illustrating host-adaptation linked to missing functions. Availability of S. aureus subsp. anaerobius genome could prompt the development of post-genomic tools for its rapid discrimination from S. aureus. |
format | Online Article Text |
id | pubmed-3910551 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Michigan State University |
record_format | MEDLINE/PubMed |
spelling | pubmed-39105512014-02-05 Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence Elbir, Haitham Robert, Catherine Nguyen, Ti Thien Gimenez, Grégory El Sanousi, Sulieman M. Flock, Jan-Ingmar Raoult, Didier Drancourt, Michel Stand Genomic Sci Short Genome Reports Staphylococcus aureus subsp. anaerobius is responsible for Morel's disease in animals and a cause of abscess in humans. It is characterized by a microaerophilic growth, contrary to the other strains of S. aureus. The 2,604,446-bp genome (32.7% GC content) of S. anaerobius ST1464 comprises one chromosome and no plasmids. The chromosome contains 2,660 open reading frames (ORFs), 49 tRNAs and three complete rRNAs, forming one complete operon. The size of ORFs ranges between 100 to 4,600 bp except for two ORFs of 6,417 and 7,173 bp encoding segregation ATPase and non-ribosomal peptide synthase, respectively. The chromosome harbors Staphylococcus phage 2638A genome and incomplete Staphylococcus phage genome PT1028, but no detectable CRISPRS. The antibiotic resistance gene for tetracycline was found although Staphylococcus aureus subsp. anaerobius is susceptible to tetracycline in-vitro. Intact oxygen detoxification genes encode superoxide dismutase and cytochrome quinol oxidase whereas the catalase gene is impaired by a stop codon. Based on the genome, in-silico multilocus sequence typing indicates that S. aureus subsp. anaerobius emerged as a clone separated from all other S. aureus strains, illustrating host-adaptation linked to missing functions. Availability of S. aureus subsp. anaerobius genome could prompt the development of post-genomic tools for its rapid discrimination from S. aureus. Michigan State University 2013-10-15 /pmc/articles/PMC3910551/ /pubmed/24501641 http://dx.doi.org/10.4056/sigs.3748294 Text en Copyright © retained by original authors http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Genome Reports Elbir, Haitham Robert, Catherine Nguyen, Ti Thien Gimenez, Grégory El Sanousi, Sulieman M. Flock, Jan-Ingmar Raoult, Didier Drancourt, Michel Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title | Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title_full | Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title_fullStr | Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title_full_unstemmed | Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title_short | Staphylococcus aureus subsp. anaerobius strain ST1464 genome sequence |
title_sort | staphylococcus aureus subsp. anaerobius strain st1464 genome sequence |
topic | Short Genome Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910551/ https://www.ncbi.nlm.nih.gov/pubmed/24501641 http://dx.doi.org/10.4056/sigs.3748294 |
work_keys_str_mv | AT elbirhaitham staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT robertcatherine staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT nguyentithien staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT gimenezgregory staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT elsanousisuliemanm staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT flockjaningmar staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT raoultdidier staphylococcusaureussubspanaerobiusstrainst1464genomesequence AT drancourtmichel staphylococcusaureussubspanaerobiusstrainst1464genomesequence |