Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae

BACKGROUND: Cysteine protease inhibitors of Brugia malayi have been ascribed to be involved in parasite development as well as to immunomodulate the host’s immune response. In Onchocerca volvulus, Onchocystatin has been shown to induce partial protection in the mouse diffusion chamber vaccination mo...

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Detalles Bibliográficos
Autores principales: Arumugam, Sridhar, Zhan, Bin, Abraham, David, Ward, Danielle, Lustigman, Sara, Klei, Thomas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910689/
https://www.ncbi.nlm.nih.gov/pubmed/24450869
http://dx.doi.org/10.1186/1756-3305-7-43

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