Cargando…
The Failure in the Stabilization of Glioblastoma-Derived Cell Lines: Spontaneous In Vitro Senescence as the Main Culprit
Cell line analysis is an important element of cancer research. Despite the progress in glioblastoma cell culturing, the cells isolated from the majority of specimens cannot be propagated infinitely in vitro. The aim of this study was to identify the processes responsible for the stabilization failur...
Autores principales: | Stoczynska-Fidelus, Ewelina, Piaskowski, Sylwester, Bienkowski, Michal, Banaszczyk, Mateusz, Hulas-Bigoszewska, Krystyna, Winiecka-Klimek, Marta, Radomiak-Zaluska, Anna, Och, Waldemar, Borowiec, Maciej, Zieba, Jolanta, Treda, Cezary, Rieske, Piotr |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910690/ https://www.ncbi.nlm.nih.gov/pubmed/24498027 http://dx.doi.org/10.1371/journal.pone.0087136 |
Ejemplares similares
-
PIN3 duplication may be partially responsible for TP53 haploinsufficiency
por: Winiecka-Klimek, Marta, et al.
Publicado: (2014) -
Different mutational characteristics of TSG in cell lines and surgical specimens
por: Stoczynska-Fidelus, Ewelina, et al.
Publicado: (2014) -
SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence
por: Winiecka-Klimek, Marta, et al.
Publicado: (2015) -
Genetic heterogeneity of RPMI-8402, a T-acute lymphoblastic leukemia cell line
por: STOCZYNSKA-FIDELUS, EWELINA, et al.
Publicado: (2016) -
Cell line with endogenous EGFR(vIII) expression is a suitable model for research and drug development purposes
por: Stec, Wojciech J., et al.
Publicado: (2016)