GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting

A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin resistance as 98% (95% confidence interval [CI], 97 to 99), based on results from earlier test versions. The measured positive predictive value of the new generation test from programmatic implementation in Cape Town, Sout...

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Detalles Bibliográficos
Autores principales: Osman, Muhammad, Simpson, John A., Caldwell, Judy, Bosman, Marlein, Nicol, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911341/
https://www.ncbi.nlm.nih.gov/pubmed/24478501
http://dx.doi.org/10.1128/JCM.02517-13
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author Osman, Muhammad
Simpson, John A.
Caldwell, Judy
Bosman, Marlein
Nicol, Mark P.
author_facet Osman, Muhammad
Simpson, John A.
Caldwell, Judy
Bosman, Marlein
Nicol, Mark P.
author_sort Osman, Muhammad
collection PubMed
description A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin resistance as 98% (95% confidence interval [CI], 97 to 99), based on results from earlier test versions. The measured positive predictive value of the new generation test from programmatic implementation in Cape Town, South Africa, was 99.5% (95% CI, 98.5 to 100), confirming excellent specificity.
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spelling pubmed-39113412014-02-13 GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting Osman, Muhammad Simpson, John A. Caldwell, Judy Bosman, Marlein Nicol, Mark P. J Clin Microbiol Mycobacteriology and Aerobic Actinomycetes A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin resistance as 98% (95% confidence interval [CI], 97 to 99), based on results from earlier test versions. The measured positive predictive value of the new generation test from programmatic implementation in Cape Town, South Africa, was 99.5% (95% CI, 98.5 to 100), confirming excellent specificity. American Society for Microbiology 2014-02 /pmc/articles/PMC3911341/ /pubmed/24478501 http://dx.doi.org/10.1128/JCM.02517-13 Text en Copyright © 2014 Osman et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Mycobacteriology and Aerobic Actinomycetes
Osman, Muhammad
Simpson, John A.
Caldwell, Judy
Bosman, Marlein
Nicol, Mark P.
GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title_full GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title_fullStr GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title_full_unstemmed GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title_short GeneXpert MTB/RIF Version G4 for Identification of Rifampin-Resistant Tuberculosis in a Programmatic Setting
title_sort genexpert mtb/rif version g4 for identification of rifampin-resistant tuberculosis in a programmatic setting
topic Mycobacteriology and Aerobic Actinomycetes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911341/
https://www.ncbi.nlm.nih.gov/pubmed/24478501
http://dx.doi.org/10.1128/JCM.02517-13
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