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Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

BACKGROUND: Genome-wide microarrays have been useful for predicting chemical-genetic interactions at the gene level. However, interpreting genome-wide microarray results can be overwhelming due to the vast output of gene expression data combined with off-target transcriptional responses many times i...

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Detalles Bibliográficos
Autores principales: Christadore, Lisa M, Pham, Lisa, Kolaczyk, Eric D, Schaus, Scott E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911882/
https://www.ncbi.nlm.nih.gov/pubmed/24444313
http://dx.doi.org/10.1186/1752-0509-8-7