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Circadian Rhythms of PER2::LUC in Individual Primary Mouse Hepatocytes and Cultures

BACKGROUND: Hepatocytes, the parenchymal cells of the liver, express core clock genes, such as Period2 and Cryptochrome2, which are involved in the transcriptional/translational feedback loop of the circadian clock. Whether or not the liver is capable of sustaining rhythms independent of a central p...

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Detalles Bibliográficos
Autores principales: Guenthner, Casey J., Luitje, Martha E., Pyle, Lorna A., Molyneux, Penny C., Yu, Jimmy K., Li, Alexander S., Leise, Tanya L., Harrington, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911982/
https://www.ncbi.nlm.nih.gov/pubmed/24498336
http://dx.doi.org/10.1371/journal.pone.0087573