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Circadian Rhythms of PER2::LUC in Individual Primary Mouse Hepatocytes and Cultures
BACKGROUND: Hepatocytes, the parenchymal cells of the liver, express core clock genes, such as Period2 and Cryptochrome2, which are involved in the transcriptional/translational feedback loop of the circadian clock. Whether or not the liver is capable of sustaining rhythms independent of a central p...
Autores principales: | Guenthner, Casey J., Luitje, Martha E., Pyle, Lorna A., Molyneux, Penny C., Yu, Jimmy K., Li, Alexander S., Leise, Tanya L., Harrington, Mary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911982/ https://www.ncbi.nlm.nih.gov/pubmed/24498336 http://dx.doi.org/10.1371/journal.pone.0087573 |
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