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Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5
CCCTC-binding factor (CTCF) can both activate as well as inhibit transcription by forming chromatin loops between regulatory regions and promoters. In this regard, Ctcf binding on non-methylated DNA and its interaction with the Cohesin complex results in differential regulation of the H19/Igf2 locus...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911986/ https://www.ncbi.nlm.nih.gov/pubmed/24498324 http://dx.doi.org/10.1371/journal.pone.0087448 |