Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy

The stratum lacunosum moleculare (SLM) is the connection hub between entorhinal cortex and hippocampus, two brain regions that are most vulnerable in Alzheimer’s disease. We recently identified a specific synaptic deficit of Nectin-3 in transgenic models for tauopathy. Here we defined cognitive impa...

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Detalles Bibliográficos
Autores principales: Maurin, Hervé, Chong, Seon-Ah, Kraev, Igor, Davies, Heather, Kremer, Anna, Seymour, Claire Marie, Lechat, Benoit, Jaworski, Tomasz, Borghgraef, Peter, Devijver, Herman, Callewaert, Geert, Stewart, Michael G., Van Leuven, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912020/
https://www.ncbi.nlm.nih.gov/pubmed/24498342
http://dx.doi.org/10.1371/journal.pone.0087605

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