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Caveolin-1 Is a Critical Determinant of Autophagy, Metabolic Switching, and Oxidative Stress in Vascular Endothelium
Caveolin-1 is a scaffolding/regulatory protein that interacts with diverse signaling molecules. Caveolin-1(null) mice have marked metabolic abnormalities, yet the underlying molecular mechanisms are incompletely understood. We found the redox stress plasma biomarker plasma 8-isoprostane was elevated...
Autores principales: | Shiroto, Takashi, Romero, Natalia, Sugiyama, Toru, Sartoretto, Juliano L., Kalwa, Hermann, Yan, Zhonghua, Shimokawa, Hiroaki, Michel, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912129/ https://www.ncbi.nlm.nih.gov/pubmed/24498385 http://dx.doi.org/10.1371/journal.pone.0087871 |
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