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AST-120 for the management of progression of chronic kidney disease

Uremic toxins such as indoxyl sulfate contribute to the pathogenesis of chronic kidney disease (CKD) by promoting glomerulosclerosis and interstitial fibrosis with loss of nephrons and vascular damage. AST-120, an orally administered intestinal sorbent, adsorbs indole, a precursor of indoxyl sulfate...

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Detalles Bibliográficos
Autores principales:	Schulman, Gerald, Vanholder, Raymond, Niwa, Toshimitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912158/ https://www.ncbi.nlm.nih.gov/pubmed/24501542 http://dx.doi.org/10.2147/IJNRD.S41339

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