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Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs
Sphingolipids are essential components in eukaryotes and have various cellular functions. Recent developments in genome-editing technologies have facilitated gene disruption in various organisms and cell lines. We here show the disruption of various sphingolipid metabolic genes in human cervical car...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912166/ https://www.ncbi.nlm.nih.gov/pubmed/24498430 http://dx.doi.org/10.1371/journal.pone.0088124 |