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Controllability Analysis of Protein Glycosylation in Cho Cells
To function as intended in vivo, a majority of biopharmaceuticals require specific glycan distributions. However, achieving a precise glycan distribution during manufacturing can be challenging because glycosylation is a non-template driven cellular process, with the potential for significant uncont...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912168/ https://www.ncbi.nlm.nih.gov/pubmed/24498415 http://dx.doi.org/10.1371/journal.pone.0087973 |