Cargando…

Ethyl Pyruvate Pretreatment Attenuates Concanavalin A-Induced Autoimmune Hepatitis in Mice

PHARMACOLOGICAL RELEVANCE: Ethyl pyruvate (EP), a potent reactive oxygen species scavenger, has been reported to contribute to the inflammatory process. However, the protective effect of ethyl pyruvate on Concanavalin A (Con A)-induced autoimmune hepatitis have not been explored. Thus, the aims of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Miao, Lu, Jie, Cheng, Ping, Lin, Chunlei, Dai, Weiqi, Wang, Fan, Wang, Chengfen, Zhang, Yan, Chen, Kan, Xu, Ling, Zhou, Yinqun, Guo, Chuanyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912171/ https://www.ncbi.nlm.nih.gov/pubmed/24498418 http://dx.doi.org/10.1371/journal.pone.0087977

Ejemplares similares

Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy
por: Shen, Miao, et al.
Publicado: (2013)

Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis
por: Cheng, Ping, et al.
Publicado: (2014)

Corrigendum to “Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy”
por: Shen, Miao, et al.
Publicado: (2016)

Protective Effects of N-Acetylcysteine in Concanavalin A-Induced Hepatitis in Mice
por: Wang, Chengfen, et al.
Publicado: (2015)

Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice
por: Zhou, Yingqun, et al.
Publicado: (2013)

Combination Therapy of Ursodeoxycholic Acid and Corticosteroids for Primary Biliary Cirrhosis with Features of Autoimmune Hepatitis: A Meta-Analysis
por: Zhang, Yan, et al.
Publicado: (2013)

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3
por: Li, Sainan, et al.
Publicado: (2016)

The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice
por: Zhou, Yingqun, et al.
Publicado: (2015)

Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity
por: Mo, Wenhui, et al.
Publicado: (2018)

Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway
por: Liu, Tong, et al.
Publicado: (2016)

Resveratrol Pretreatment Attenuates Concanavalin A-induced Hepatitis through Reverse of Aberration in the Immune Response and Regenerative Capacity in Aged Mice
por: Huang, Tse-Hung, et al.
Publicado: (2017)

Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis
por: Gajić, Dragica, et al.
Publicado: (2021)

Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice
por: Li, Jingjing, et al.
Publicado: (2015)

GIT2 deficiency attenuates concanavalin A-induced hepatitis in mice
por: Hao, Yu-E, et al.
Publicado: (2015)

Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury
por: Feng, Jiao, et al.
Publicado: (2018)

Ethyl pyruvate, a versatile protector in inflammation and autoimmunity
por: Koprivica, Ivan, et al.
Publicado: (2022)

Hydrogen Sulfide Ameliorates Ischemia/Reperfusion-Induced Hepatitis by Inhibiting Apoptosis and Autophagy Pathways
por: Cheng, Ping, et al.
Publicado: (2014)

Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis
por: Yang, Wenchang, et al.
Publicado: (2022)

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway
por: Wu, Liwei, et al.
Publicado: (2017)

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice
por: Mao, Yuqing, et al.
Publicado: (2015)

Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate
por: Najafi, Gholamreza, et al.
Publicado: (2016)

Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook
por: Liu, Yang, et al.
Publicado: (2022)

N-Acetylcysteine Attenuates Ischemia-Reperfusion-Induced Apoptosis and Autophagy in Mouse Liver via Regulation of the ROS/JNK/Bcl-2 Pathway
por: Wang, Chengfen, et al.
Publicado: (2014)

Multi-Omics Analysis Reveals the Protection of Gasdermin D in Concanavalin A-Induced Autoimmune Hepatitis
por: Wang, Kaicen, et al.
Publicado: (2022)

Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis
por: Li, Jingjing, et al.
Publicado: (2015)

Salidroside Attenuates Concanavalin A-Induced Hepatitis via Modulating Cytokines Secretion and Lymphocyte Migration in Mice
por: Hu, Baoji, et al.
Publicado: (2014)

15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity
por: Chen, Kan, et al.
Publicado: (2014)

Erratum to “15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity”
por: Chen, Kan, et al.
Publicado: (2014)

Ethyl pyruvate attenuates formalin-induced inflammatory nociception by inhibiting neuronal ERK phosphorylation
por: Lee, Min Jung, et al.
Publicado: (2012)

The Synergistic In Vitro and In Vivo Antitumor Effect of Combination Therapy with Salinomycin and 5-Fluorouracil against Hepatocellular Carcinoma
por: Wang, Fan, et al.
Publicado: (2014)

Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway
por: Cheng, Ziqi, et al.
Publicado: (2021)

Rescue of autoimmune hepatitis by soluble MHC class II molecules in an altered concanavalin A‐induced experimental model
por: Bakela, Katerina, et al.
Publicado: (2020)

Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation
por: Lee, D H, et al.
Publicado: (2016)

Diagnostic Performance of Des-γ-carboxy Prothrombin for Hepatocellular Carcinoma: A Meta-Analysis
por: Zhu, Rong, et al.
Publicado: (2014)

Protective Effect of Astaxanthin on Liver Fibrosis through Modulation of TGF-β1 Expression and Autophagy
por: Shen, Miao, et al.
Publicado: (2014)

Ethyl pyruvate attenuates delayed experimental cerebral vasospasm following subarachnoid haemorrhage in rats: possible role of JNK pathway
por: Jin, Ke, et al.
Publicado: (2018)

Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy
por: Wang, Wenwen, et al.
Publicado: (2019)

Impact of ethyl pyruvate on Adriamycin-induced cardiomyopathy in rats
por: Liu, Menglin, et al.
Publicado: (2016)

Ethyl Pyruvate Induces Tolerogenic Dendritic Cells
por: Djedovic, Neda, et al.
Publicado: (2019)

Stem cells from human exfoliated deciduous teeth ameliorate concanavalin A-induced autoimmune hepatitis by protecting hepatocytes from apoptosis
por: Zhou, Yi-Kun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vt7fl4eife55lesmg8baiph2pp