Cargando…
Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
The incidence of human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) has rapidly increased over the past 30 years prompting the suggestion that an epidemic may be on the horizon. Therefore, there is a clinical need to develop alternate therapeutic strategies to manage t...
Autores principales: | Xie, Xiujie, Piao, Longzhu, Bullock, Brooke N., Smith, Ashley, Su, Tizhi, Zhang, Manchao, Teknos, Theodoros N., Arora, Paramjit S., Pan, Quintin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912227/ https://www.ncbi.nlm.nih.gov/pubmed/23474763 http://dx.doi.org/10.1038/onc.2013.25 |
Ejemplares similares
-
Repositioning Fenofibrate to Reactivate p53 and Reprogram the Tumor-Immune Microenvironment in HPV+ Head and Neck Squamous Cell Carcinoma
por: O’Neill, W. Quinn, et al.
Publicado: (2022) -
TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma
por: Piao, Longzhu, et al.
Publicado: (2016) -
Phosphorylation of Nanog is Essential to Regulate Bmi1 and Promote Tumorigenesis
por: Xie, Xiujie, et al.
Publicado: (2013) -
PKCε Phosphorylates and Mediates the Cell Membrane Localization of RhoA
por: Su, Tizhi, et al.
Publicado: (2013) -
p53 functional states are associated with distinct aldehyde dehydrogenase transcriptomic signatures
por: Gui, Shanying, et al.
Publicado: (2020)