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Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development
The maternal nucleolus is required for proper activation of the embryonic genome (EGA) and early embryonic development. Nucleologenesis is characterized by the transformation of a nucleolar precursor body (NPB) to a mature nucleolus during preimplantation development. However, the function of NPBs a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912245/ https://www.ncbi.nlm.nih.gov/pubmed/23172912 http://dx.doi.org/10.1242/dev.083279 |