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Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis

BACKGROUND: CXCL12/CXCR4 transactivation of epidermal growth factor family receptors in lipid raft membrane microdomains on cell surface is thought to mediate tumor growth and subsequent development of metastatic disease. CTCE-9908 is a known inhibitor of CXCR4. Herein, we tested the efficacy of CTC...

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Detalles Bibliográficos
Autores principales:	Wong, Donald, Kandagatla, Pridvi, Korz, Walter, Chinni, Sreenivasa R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912255/ https://www.ncbi.nlm.nih.gov/pubmed/24472670 http://dx.doi.org/10.1186/1471-2490-14-12

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