Cargando…

A Primer on Effectiveness and Efficacy Trials

Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs. Unfortunately, the distinction between these two types of trials is often poorly understood. In this primer, we highlight several differences b...

Descripción completa

Detalles Bibliográficos
Autores principales: Singal, Amit G, Higgins, Peter D R, Waljee, Akbar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912314/
https://www.ncbi.nlm.nih.gov/pubmed/24384867
http://dx.doi.org/10.1038/ctg.2013.13
Descripción
Sumario:Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs. Unfortunately, the distinction between these two types of trials is often poorly understood. In this primer, we highlight several differences between these two types of trials including study design, patient populations, intervention design, data analysis, and result reporting.