Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease

OBJECTIVES: The NOS2 gene encodes for the inducible nitric oxide synthase (iNOS), responsible for nitric oxide (NO) production, which contributes to antimicrobial and antipathogenic activities. Higher levels of both iNOS and NO-induced damage have been observed in inflammatory bowel disease (IBD) pa...

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Detalles Bibliográficos
Autores principales: Dhillon, Sandeep S, Mastropaolo, Lucas A, Murchie, Ryan, Griffiths, Christopher, Thöni, Cornelia, Elkadri, Abdul, Xu, Wei, Mack, Amanda, Walters, Thomas, Guo, Conghui, Mack, David, Huynh, Hien, Baksh, Shairaz, Silverberg, Mark S, Brumell, John H, Snapper, Scott B, Muise, Aleixo M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912315/
https://www.ncbi.nlm.nih.gov/pubmed/24430113
http://dx.doi.org/10.1038/ctg.2013.17

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