Two Interconvertible Folds Modulate the Activity of a DNA Aptamer Against Transferrin Receptor

Thanks to their ability to recognize biomolecular targets with high affinity and specificity, nucleic acid aptamers are increasingly investigated as diagnostic and therapeutic tools, particularly when their targets are cell-surface receptors. Here, we investigate the relationship between the folding...

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Detalles Bibliográficos
Autores principales: Porciani, David, Signore, Giovanni, Marchetti, Laura, Mereghetti, Paolo, Nifosì, Riccardo, Beltram, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912326/
https://www.ncbi.nlm.nih.gov/pubmed/24472870
http://dx.doi.org/10.1038/mtna.2013.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912326/
https://www.ncbi.nlm.nih.gov/pubmed/24472870
http://dx.doi.org/10.1038/mtna.2013.71

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