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Two Interconvertible Folds Modulate the Activity of a DNA Aptamer Against Transferrin Receptor
Thanks to their ability to recognize biomolecular targets with high affinity and specificity, nucleic acid aptamers are increasingly investigated as diagnostic and therapeutic tools, particularly when their targets are cell-surface receptors. Here, we investigate the relationship between the folding...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912326/ https://www.ncbi.nlm.nih.gov/pubmed/24472870 http://dx.doi.org/10.1038/mtna.2013.71 |