Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) has heterogeneous clinical and biological behavior. Whole-genome and -exome sequencing has contributed to the characterization of the mutational spectrum of the disease, but the underlying transcriptional profile is still poorly understood. We have performed deep R...

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Detalles Bibliográficos
Autores principales: Ferreira, Pedro G., Jares, Pedro, Rico, Daniel, Gómez-López, Gonzalo, Martínez-Trillos, Alejandra, Villamor, Neus, Ecker, Simone, González-Pérez, Abel, Knowles, David G., Monlong, Jean, Johnson, Rory, Quesada, Victor, Djebali, Sarah, Papasaikas, Panagiotis, López-Guerra, Mónica, Colomer, Dolors, Royo, Cristina, Cazorla, Maite, Pinyol, Magda, Clot, Guillem, Aymerich, Marta, Rozman, Maria, Kulis, Marta, Tamborero, David, Gouin, Anaïs, Blanc, Julie, Gut, Marta, Gut, Ivo, Puente, Xose S., Pisano, David G., Martin-Subero, José Ignacio, López-Bigas, Nuria, López-Guillermo, Armando, Valencia, Alfonso, López-Otín, Carlos, Campo, Elías, Guigó, Roderic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912412/
https://www.ncbi.nlm.nih.gov/pubmed/24265505
http://dx.doi.org/10.1101/gr.152132.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912412/
https://www.ncbi.nlm.nih.gov/pubmed/24265505
http://dx.doi.org/10.1101/gr.152132.112

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