Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells

Both diffusible factors acting in trans and chromatin components acting in cis are implicated in gene regulation, but the extent to which either process causally determines a cell's transcriptional identity is unclear. We recently used cell fusion to define a class of silent genes termed “cis-s...

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Detalles Bibliográficos
Autores principales: Looney, Timothy J., Zhang, Li, Chen, Chih-Hsin, Lee, Jae Hyun, Chari, Sheila, Mao, Frank Fuxiang, Pelizzola, Mattia, Zhang, Lu, Lister, Ryan, Baker, Samuel W., Fernandes, Croydon J., Gaetz, Jedidiah, Foshay, Kara M., Clift, Kayla L., Zhang, Zhenyu, Li, Wei-Qiang, Vallender, Eric J., Wagner, Ulrich, Qin, Jane Yuxia, Michelini, Katelyn J., Bugarija, Branimir, Park, Donghyun, Aryee, Emmanuel, Stricker, Thomas, Zhou, Jie, White, Kevin P., Ren, Bing, Schroth, Gary P., Ecker, Joseph R., Xiang, Andy Peng, Lahn, Bruce T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912417/
https://www.ncbi.nlm.nih.gov/pubmed/24310002
http://dx.doi.org/10.1101/gr.143891.112

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