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Expression of codon optimized genes in microbial systems: current industrial applications and perspectives
The efficient production of functional proteins in heterologous hosts is one of the major bases of modern biotechnology. Unfortunately, many genes are difficult to express outside their original context. Due to their apparent “silent” nature, synonymous codon substitutions have long been thought to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912506/ https://www.ncbi.nlm.nih.gov/pubmed/24550894 http://dx.doi.org/10.3389/fmicb.2014.00021 |