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Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion

Ablation of the mitochondrial fusion and endoplasmic reticulum (ER)–tethering protein Mfn2 causes ER stress, but whether this is just an epiphenomenon of mitochondrial dysfunction or a contributor to the phenotypes in mitofusin (Mfn)-depleted Drosophila melanogaster is unclear. In this paper, we sho...

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Detalles Bibliográficos
Autores principales: Debattisti, Valentina, Pendin, Diana, Ziviani, Elena, Daga, Andrea, Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912536/
https://www.ncbi.nlm.nih.gov/pubmed/24469638
http://dx.doi.org/10.1083/jcb.201306121