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Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients

Purpose. To determine whether the rate of graft detachment in patients undergoing the DSAEK procedure is influenced by the time elapsed between donor death and tissue implantation. Methods. Data on procedure outcome and donor tissue for patients undergoing the DSAEK procedure were reviewed. Data on...

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Autores principales: Demsey, Daniel, Baxter, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912621/
https://www.ncbi.nlm.nih.gov/pubmed/24555119
http://dx.doi.org/10.5402/2011/831051
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author Demsey, Daniel
Baxter, Stephanie
author_facet Demsey, Daniel
Baxter, Stephanie
author_sort Demsey, Daniel
collection PubMed
description Purpose. To determine whether the rate of graft detachment in patients undergoing the DSAEK procedure is influenced by the time elapsed between donor death and tissue implantation. Methods. Data on procedure outcome and donor tissue for patients undergoing the DSAEK procedure were reviewed. Data on time elapsed between harvest, processing, storage, and implantation of the tissue, as well as donor tissue endothelial cell count were obtained from reports made available from the Eye Bank of Canada. The adverse outcome of interest was graft detachment. Results. 71 cases were reviewed, with 14% resulting in detachment. The following time periods were compared between detachment and nondetachment groups: donor death to enucleation; enucleation to processing; duration of storage at the Eye Bank to implantation. No statistically significant differences were found (Student's t-test, P > 0.05). Endothelial cell counts of donor tissue were compared between the two groups, and no statistically significant difference was found (Student's t-test, P > 0.05). Conclusion. The range of processing times and endothelial cell counts in donor tissue available from the Eye Bank did not predict a change in the rate of graft dislocation in one surgeon's practice.
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spelling pubmed-39126212014-02-19 Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients Demsey, Daniel Baxter, Stephanie ISRN Ophthalmol Research Article Purpose. To determine whether the rate of graft detachment in patients undergoing the DSAEK procedure is influenced by the time elapsed between donor death and tissue implantation. Methods. Data on procedure outcome and donor tissue for patients undergoing the DSAEK procedure were reviewed. Data on time elapsed between harvest, processing, storage, and implantation of the tissue, as well as donor tissue endothelial cell count were obtained from reports made available from the Eye Bank of Canada. The adverse outcome of interest was graft detachment. Results. 71 cases were reviewed, with 14% resulting in detachment. The following time periods were compared between detachment and nondetachment groups: donor death to enucleation; enucleation to processing; duration of storage at the Eye Bank to implantation. No statistically significant differences were found (Student's t-test, P > 0.05). Endothelial cell counts of donor tissue were compared between the two groups, and no statistically significant difference was found (Student's t-test, P > 0.05). Conclusion. The range of processing times and endothelial cell counts in donor tissue available from the Eye Bank did not predict a change in the rate of graft dislocation in one surgeon's practice. International Scholarly Research Network 2011-10-25 /pmc/articles/PMC3912621/ /pubmed/24555119 http://dx.doi.org/10.5402/2011/831051 Text en Copyright © 2011 D. Demsey and S. Baxter. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Demsey, Daniel
Baxter, Stephanie
Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title_full Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title_fullStr Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title_full_unstemmed Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title_short Influence of Donor Tissue Factors on Detachment Rate in DSAEK Patients
title_sort influence of donor tissue factors on detachment rate in dsaek patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912621/
https://www.ncbi.nlm.nih.gov/pubmed/24555119
http://dx.doi.org/10.5402/2011/831051
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