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The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells
Cancer cells frequently exploit the IGF signaling, a fundamental pathway mediating development, cell growth, and survival. As a consequence, several components of the IGF signaling are deregulated in cancer and sustain cancer progression. However, specific targeting of IGF-IR in humans has resulted...
Autores principales: | Malaguarnera, Roberta, Belfiore, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912738/ https://www.ncbi.nlm.nih.gov/pubmed/24550888 http://dx.doi.org/10.3389/fendo.2014.00010 |
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