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HMGB1 Is Involved in the Protective Effect of the PPARα Agonist Fenofibrate against Cardiac Hypertrophy

High mobility group box 1 (HMGB1) is a ubiquitous nuclear DNA-binding protein whose function is dependent on its cellular location. Extracellular HMGB1 is regarded as a delayed mediator of proinflammatory cytokines for initiating and amplifying inflammatory responses, whereas nuclear HMGB1 has been...

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Detalles Bibliográficos
Autores principales: Jia, Zhankui, Xue, Rui, Liu, Gangqiong, Li, Ling, Yang, Jinjian, Pi, Guofu, Ma, Shengli, Kan, Quancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913009/
https://www.ncbi.nlm.nih.gov/pubmed/24523730
http://dx.doi.org/10.1155/2014/541394

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