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Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

OBJECTIVES: Stratified medicine is often heralded as the future of clinical practice. Key part of stratified medicine is the use of predictive biomarkers, which identify patient subgroups most likely to benefit (or least likely to experience harm) from an intervention. We investigated how many and w...

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Detalles Bibliográficos
Autores principales: Malottki, Kinga, Biswas, Mousumi, Deeks, Jonathan J, Riley, Richard D, Craddock, Charles, Johnson, Philip, Billingham, Lucinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913033/
https://www.ncbi.nlm.nih.gov/pubmed/24468721
http://dx.doi.org/10.1136/bmjopen-2013-004188