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Evaluation of Novel Fetal Hemoglobin Inducer Drugs in Treatment of β-Hemoglobinopathy Disorders

OBJECTIVE: The use of fetal hemoglobin (HbF) inducer drugs is considered as a novel approach in treatment of β-hemoglobinopathies, especially β- thalassemia and sickle cell disease. HbF inducers including hydroxyurea, histone deacetylase (HDAC) inhibitor agents such as sodium butyrate, azacitidine,...

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Detalles Bibliográficos
Autores principales: Fard, Ali Dehghani, Hosseini, Seyed Ahmad, Shahjahani, Mohammad, Salari, Fatemeh, Jaseb, Kaveh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913144/
https://www.ncbi.nlm.nih.gov/pubmed/24505535