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Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs

Potent induction of fetal hemoglobin (HbF) production results in alleviating the complications of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. Janus kinase/Signal transducer and activator of transcriptio...

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Detalles Bibliográficos
Autores principales: Rahim, Fakher, Allahmoradi, Hossein, Salari, Fatemeh, Shahjahani, Mohammad, Fard, Ali Dehghani, Hosseini, Seyed Ahmad, Mousakhani, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913148/
https://www.ncbi.nlm.nih.gov/pubmed/24505534