Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer

Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory met...

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Autores principales: Nalabolu, Mohan Reddy, Palasamudram, Kalyani, Jamil, Kaiser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913152/
https://www.ncbi.nlm.nih.gov/pubmed/24505549
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author Nalabolu, Mohan Reddy
Palasamudram, Kalyani
Jamil, Kaiser
author_facet Nalabolu, Mohan Reddy
Palasamudram, Kalyani
Jamil, Kaiser
author_sort Nalabolu, Mohan Reddy
collection PubMed
description Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. Leptin and Adiponectin pathways are involved in proliferation process in breast cancer. Current review describes potential relationship between the molecular actions and clinical significance of leptin and adiponectin in breast cancer.
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spelling pubmed-39131522014-02-06 Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer Nalabolu, Mohan Reddy Palasamudram, Kalyani Jamil, Kaiser Int J Hematol Oncol Stem Cell Res Review Article Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. Leptin and Adiponectin pathways are involved in proliferation process in breast cancer. Current review describes potential relationship between the molecular actions and clinical significance of leptin and adiponectin in breast cancer. Tehran University of Medical Sciences 2014 /pmc/articles/PMC3913152/ /pubmed/24505549 Text en © 2014 Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Review Article
Nalabolu, Mohan Reddy
Palasamudram, Kalyani
Jamil, Kaiser
Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title_full Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title_fullStr Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title_full_unstemmed Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title_short Adiponectin and Leptin Molecular Actions and Clinical Significance in Breast Cancer
title_sort adiponectin and leptin molecular actions and clinical significance in breast cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913152/
https://www.ncbi.nlm.nih.gov/pubmed/24505549
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