Characterization of a modified ROCK2 protein that allows use of N6-ATP analogs for the identification of novel substrates

BACKGROUND: The Rho-associated coiled-coil kinase-2 (ROCK2) is an important signaling transducer in the transmission of extracellular signals effecting organization of the actin cytoskeleton. ROCK2 has been implicated in numerous pathologies and the current focus is on understanding the molecular ev...

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Detalles Bibliográficos
Autores principales: Couzens, Amber L, Gill, R Montgomery, Scheid, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913329/
https://www.ncbi.nlm.nih.gov/pubmed/24405853
http://dx.doi.org/10.1186/1472-6750-14-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913329/
https://www.ncbi.nlm.nih.gov/pubmed/24405853
http://dx.doi.org/10.1186/1472-6750-14-2

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