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A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells

Cytocompatibility of repair materials plays a significant role in the success of root canal repair. We conducted a comparative study on the cytocompatibility among iRoot BP Plus, iRoot FS, ProRoot MTA, and Super-EBA in L929 cells and MG63 cells. The results revealed that iRoot FS was able to complet...

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Detalles Bibliográficos
Autores principales: Jiang, Yuqing, Zheng, Qinghua, Zhou, Xuedong, Gao, Yuan, Huang, Dingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913516/
https://www.ncbi.nlm.nih.gov/pubmed/24526893
http://dx.doi.org/10.1155/2014/463826
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author Jiang, Yuqing
Zheng, Qinghua
Zhou, Xuedong
Gao, Yuan
Huang, Dingming
author_facet Jiang, Yuqing
Zheng, Qinghua
Zhou, Xuedong
Gao, Yuan
Huang, Dingming
author_sort Jiang, Yuqing
collection PubMed
description Cytocompatibility of repair materials plays a significant role in the success of root canal repair. We conducted a comparative study on the cytocompatibility among iRoot BP Plus, iRoot FS, ProRoot MTA, and Super-EBA in L929 cells and MG63 cells. The results revealed that iRoot FS was able to completely solidify within 1 hour. iRoot BP Plus required 7-day incubation, which was much longer than expected (2 hours), to completely set. ProRoot MTA and Super-EBA exhibited a similar setting duration of 12 hours. All the materials except Super-EBA possessed negligible in vitro cytotoxicity. iRoot FS had the best cell adhesion capacity in both L929 and MG63 cells. With rapid setting, negligible cytotoxicity, and enhanced cell adhesion capacity, iRoot FS demonstrated great potential in clinical applications. Future work should focus on longer-term in vitro cytocompatibility and an in vivo assessment.
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spelling pubmed-39135162014-02-13 A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells Jiang, Yuqing Zheng, Qinghua Zhou, Xuedong Gao, Yuan Huang, Dingming ScientificWorldJournal Research Article Cytocompatibility of repair materials plays a significant role in the success of root canal repair. We conducted a comparative study on the cytocompatibility among iRoot BP Plus, iRoot FS, ProRoot MTA, and Super-EBA in L929 cells and MG63 cells. The results revealed that iRoot FS was able to completely solidify within 1 hour. iRoot BP Plus required 7-day incubation, which was much longer than expected (2 hours), to completely set. ProRoot MTA and Super-EBA exhibited a similar setting duration of 12 hours. All the materials except Super-EBA possessed negligible in vitro cytotoxicity. iRoot FS had the best cell adhesion capacity in both L929 and MG63 cells. With rapid setting, negligible cytotoxicity, and enhanced cell adhesion capacity, iRoot FS demonstrated great potential in clinical applications. Future work should focus on longer-term in vitro cytocompatibility and an in vivo assessment. Hindawi Publishing Corporation 2014-01-12 /pmc/articles/PMC3913516/ /pubmed/24526893 http://dx.doi.org/10.1155/2014/463826 Text en Copyright © 2014 Yuqing Jiang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jiang, Yuqing
Zheng, Qinghua
Zhou, Xuedong
Gao, Yuan
Huang, Dingming
A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title_full A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title_fullStr A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title_full_unstemmed A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title_short A Comparative Study on Root Canal Repair Materials: A Cytocompatibility Assessment in L929 and MG63 Cells
title_sort comparative study on root canal repair materials: a cytocompatibility assessment in l929 and mg63 cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913516/
https://www.ncbi.nlm.nih.gov/pubmed/24526893
http://dx.doi.org/10.1155/2014/463826
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