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A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to be immunized without the need to sacrifice them. Th...
Autores principales: | Seeber, Stefan, Ros, Francesca, Thorey, Irmgard, Tiefenthaler, Georg, Kaluza, Klaus, Lifke, Valeria, Fischer, Jens André Alexander, Klostermann, Stefan, Endl, Josef, Kopetzki, Erhard, Pashine, Achal, Siewe, Basile, Kaluza, Brigitte, Platzer, Josef, Offner, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913575/ https://www.ncbi.nlm.nih.gov/pubmed/24503933 http://dx.doi.org/10.1371/journal.pone.0086184 |
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