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EndoS Reduces the Pathogenicity of Anti-mCOL7 IgG through Reduced Binding of Immune Complexes to Neutrophils

Endo-β-N-acetylglucosaminidase (EndoS) has been shown to act as a potent pathogen-derived immunomodulatory molecule in autoimmune diseases. Here we investigated how EndoS treatment reduces the pathogenicity of rabbit anti-mCOL7 IgG using different experimental models of epidermolysis bullosa acquisi...

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Detalles Bibliográficos
Autores principales: Yu, Xinhua, Zheng, Junfeng, Collin, Mattias, Schmidt, Enno, Zillikens, Detlef, Petersen, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913582/
https://www.ncbi.nlm.nih.gov/pubmed/24504190
http://dx.doi.org/10.1371/journal.pone.0085317