Treatment with N- and C-Terminal Peptides of Parathyroid Hormone-Related Protein Partly Compensate the Skeletal Abnormalities in IGF-I Deficient Mice

Insulin-like growth factor-I (IGF-I) deficiency causes growth delay, and IGF-I has been shown to partially mediate bone anabolism by parathyroid hormone (PTH). PTH-related protein (PTHrP) is abundant in bone, and has osteogenic features by poorly defined mechanisms. We here examined the capacity of...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-de la Rosa, Lourdes, López-Herradón, Ana, Portal-Núñez, Sergio, Murillo-Cuesta, Silvia, Lozano, Daniel, Cediel, Rafael, Varela-Nieto, Isabel, Esbrit, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913635/
https://www.ncbi.nlm.nih.gov/pubmed/24503961
http://dx.doi.org/10.1371/journal.pone.0087536

Ejemplares similares

Ejemplares similares