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EGFR-mediated tumor immunoescape: The imbalance between phosphorylated STAT1 and phosphorylated STAT3

The epidermal growth factor receptor (EGFR) supports the escape of malignant cells from immunosurveillance by inhibiting the activation of signal transducer and activator of transcription 1 (STAT1) while promoting that of STAT3. We have recently demonstrated that protein tyrosine phosphatase, non-re...

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Detalles Bibliográficos
Autores principales: Concha-Benavente, Fernando, Srivastava, Raghvendra M, Ferrone, Soldano, Ferris, Robert L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913673/
https://www.ncbi.nlm.nih.gov/pubmed/24501692
http://dx.doi.org/10.4161/onci.27215

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