KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma

Natural killer (NK) cells play a major role in antitumor immune responses. Recent results from our laboratory demonstrate the impact of the immunogenetic background on the activity of NK cells and hence on the outcome of hepatocellular carcinoma, disclosing perspectives for the development of NK-cel...

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Detalles Bibliográficos
Autores principales: Cariani, Elisabetta, Missale, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913692/
https://www.ncbi.nlm.nih.gov/pubmed/24501686
http://dx.doi.org/10.4161/onci.26622
Descripción
Sumario:Natural killer (NK) cells play a major role in antitumor immune responses. Recent results from our laboratory demonstrate the impact of the immunogenetic background on the activity of NK cells and hence on the outcome of hepatocellular carcinoma, disclosing perspectives for the development of NK-cell based therapies.

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