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Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma

Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cel...

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Detalles Bibliográficos
Autor principal: Beatty, Gregory L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913694/
https://www.ncbi.nlm.nih.gov/pubmed/24501687
http://dx.doi.org/10.4161/onci.26837
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author Beatty, Gregory L
author_facet Beatty, Gregory L
author_sort Beatty, Gregory L
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description Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cells, eventually leading to tumor regression.
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spelling pubmed-39136942014-02-05 Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma Beatty, Gregory L Oncoimmunology Author's View Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cells, eventually leading to tumor regression. Landes Bioscience 2013-12-01 2013-10-22 /pmc/articles/PMC3913694/ /pubmed/24501687 http://dx.doi.org/10.4161/onci.26837 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Beatty, Gregory L
Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_full Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_fullStr Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_full_unstemmed Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_short Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_sort macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913694/
https://www.ncbi.nlm.nih.gov/pubmed/24501687
http://dx.doi.org/10.4161/onci.26837
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